Banca de QUALIFICAÇÃO: JOSELAINE SOUTO HALL SILVA

Uma banca de QUALIFICAÇÃO de DOUTORADO foi cadastrada pelo programa.
DISCENTE : JOSELAINE SOUTO HALL SILVA
DATA : 09/03/2023
HORA: 09:00
LOCAL: Google Meet
TÍTULO:

MAMMALS RESERVOIR OF Trypanosoma sp. AND THE FAUNA OF SMALL MAMMALS IN THE NORTH PANTANAL: REVIEW OF RESEARCH IN THIS SCENARIO

PALAVRAS-CHAVES:

Trypanosomiasis; Trypanosoma cruzi; Bioaccumulators

PÁGINAS: 119
GRANDE ÁREA: Outra
ÁREA: Ciências Ambientais
RESUMO:

The changes in terrestrial ecosystems where the reservoirs and vectors of infectious diseases live pose a great challenge for the scientific field, which is to know, analyze and propose solutions for emerging and reemerging diseases. From this perspective, research has pointed to the importance of studies focusing on the ecology of diseases approaching the natural reservoirs of parasites as a means of understanding the cycle of disease transmission, the parasite-host relationships, and the mechanisms of their control. In this context, scientists have sought to understand the interactions between Trypanosoma parasites and mammals as the main taxa that acts as a natural reservoir of these protozoa. This understanding is essential to better understand the cycle of these parasites in nature and to establish mechanisms for the control of trypanosomiasis, such as Chagas disease, which mainly affects countries in South America. Thus, to gather information on mammalian reservoirs of Trypanosoma and their respective ecological occurrences, this study sought to compile data from the main publications on the subject from 2010 to 2020. 446 articles indexed in the Web of Science and Scopus from which a bibliometric analysis was carried out as well as a database that allowed a meta-analysis pointing out the main Trypanosoma harbored in mammals around the world, as well as the main taxa of mammals harboring these parasites. Finally, a point analysis was performed with mammals captured in the northern portion of the Pantanal of Mato Grosso, verifying the occurrence of T. cruzi in small mammals through tissue analysis using the qPCR (Polymerase chain reaction) technique. The main research on the topic of mammals as Trypanosoma reservoirs is concentrated in South America and was carried out with the participation of Brazilian researchers from Fiocruz, with emphasis on the leadership of researcher Ana Maria Jansen. Regarding the diversity of Trypanosoma harbored in mammals, 15 species were recorded in the 97 articles analyzed, distributed in five continents, with emphasis on the occurrence of T. cruzi, present in 85.13% of mammals positive for some Trypanosoma. The dataset of the articles reviewed resulted in 22,662 individuals belonging to 366 species in 12 mammalian orders. Of this total, 23.59% of the individuals were carriers of some Trypanosoma and 20.09% of T. cruzi, exclusively in the American continent. The large number of publications on the subject reveals the importance given to the studies of Trypanosoma reservoirs, especially in American countries where Chagas disease affects many people. The advancement of research has shown that mammals play a fundamental role in the biological cycle of several species of Trypanosoma and that the diversity of species of mammals that are potential reservoirs of these parasites is quite wide. Small mammals represent important reservoirs and their diversity for Brazil is 263 species of Rodentia and 68 of Didelphimorphia. For the North Pantanal, 42 species of Rodentia and 24 of Didelphimorphia are known, from which we obtained tissue samples of eight and 10 species respectively.

MEMBROS DA BANCA:
Interno - 61265003 - ANTONIO FRANCISCO MALHEIROS
Interno - 118188001 - ERNANDES SOBREIRA OLIVEIRA JUNIOR
Externo ao Programa - 83182001 - LUCIANA MELHORANCA MOREIRA AÑEZ
Externo à Instituição - MICHELE IGARASHI WATANABE - UFMT
Externo à Instituição - OMAR ARIEL ESPINOSA DOMÍNGUEZ - FAPAN